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EpiPen Cost With and Without Insurance in 2025

Alexis Bryan
Alexis Bryan26 Feb 2025
Reviewed and Fact Checked ✔️

EpiPen Cost With and Without Insurance in 2025

EpiPens (epinephrine auto-injectors) can be lifesaving in emergencies for those with severe allergies. Yet they remain expensive, especially for those without robust insurance coverage. Below, you’ll find updated cost estimates, state-specific coverage details, and practical tips for saving money on your EpiPen in 2025.

What Is the Average Cost of EpiPen Without Insurance?

The brand-name EpiPen typically costs around $680 for a two-pack at many pharmacies nationwide. Generic versions(often called “epinephrine auto-injectors”) average around $340–$400 for a two-pack, depending on the pharmacy and discount programs used. You’ll need a prescription from your healthcare provider to purchase either brand-name or generic options.

What This Means for You
If you have no insurance or a high-deductible plan, consider generic auto-injectors and discount programs. They can cut your costs by up to 50% or more.

What Is the Cost of Brand-Name EpiPen at Popular Pharmacies in 2025?

Below are estimates for a two-pack of brand-name EpiPen (0.3 mg) at major pharmacy chains in the U.S. Always call ahead because local prices can vary.

PharmacyEstimated Cash Price
CVS$645–$685
Walgreens$700–$740
Walmart$670–$695
Rite Aid$710–$735
Kroger$690–$730
Wegmans$690–$710
Price Chopper$690–$715

Data sourced from GoodRx cost estimates and individual pharmacy listings as of early 2025.

What Is the Cost of EpiPen Jr. at Popular Pharmacies in 2025?

EpiPen Jr (0.15 mg) is indicated for children weighing 33–66 pounds. Costs are generally similar to adult doses, but check with each pharmacy for specifics.

PharmacyEpiPen Jr. Cash Price
CVS$640–$680
Walgreens$710–$750
Walmart$660–$690
Rite Aid$695–$725
Kroger$685–$720
Wegmans$680–$710
Price Chopper$680–$715

How Do EpiPen Costs Vary by State?

Prices and coverage can also differ by state, especially if you qualify for Medicaid or other state-funded assistance. Below are 10 examples of how Medicaid in different states may cover epinephrine auto-injectors. Always check with your plan or state program for exact details.

StateMedicaid ProgramCoverage DetailsOfficial Site Link
California (CA)Medi-CalCovers epinephrine auto-injectors for most enrollees. Copays as low as $1–$5.CA DHCS Website
New York (NY)NYS MedicaidCovers brand-name and generic if medically necessary. Prior authorization may apply.NY Health Dept
Texas (TX)Texas MedicaidCovers EpiPen under outpatient prescription benefits. Quantity limits may apply.Texas Medicaid
Florida (FL)Florida MedicaidCovers both adult and junior doses; prior authorization varies by plan.Florida Medicaid
Pennsylvania (PA)PA MedicaidEpiPen is covered when medically necessary; copay typically $1–$3.PA DHS
Illinois (IL)Illinois MedicaidMost plans cover EpiPen with a nominal copay. Check formulary for restrictions.IL Healthcare & Family Services
Ohio (OH)Ohio MedicaidCovers emergency medications like EpiPen; some plans require step therapy or prior auth.Ohio Medicaid
Michigan (MI)Michigan MedicaidCovers EpiPen and generics; brand may need prior authorization.MI MDHHS
North Carolina (NC)NC MedicaidCovers epinephrine auto-injectors; cost-sharing depends on plan tier.NC Medicaid
Georgia (GA)Georgia MedicaidOffers coverage for most epinephrine auto-injectors with minimal copays.GA Medicaid

What This Means for You
If you qualify for Medicaid in your state, check its preferred drug list or formulary to see which epinephrine auto-injectors are covered at the lowest cost.

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Alexis Bryan

Alexis Bryan MPH, is a recent graduate of Columbia’s Mailman School of Public Health. She is passionate about increasing access to care to improve health outcomes. Outside of work, she loves to travel, read, and pay too much attention to her plants.

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