What’s the Difference Between Ibuprofen & Acetaminophen?

Acetaminophen and ibuprofen are more commonly referred to as Tylenol and Advil. These are their most popular brand names. Ibuprofen is an anti-inflammatory medication that reduces inflammation and pain. They can both be used to reduce fever. Acetaminophen is used for pain and to reduce fever. 

Ibuprofen vs. Acetaminophen

According to Sapna Patel, Director of Clinical Services at Mosaic Pharmacy Services, “Ibuprofen is an anti-inflammatory medication that reduces inflammation and pain. It can also be used to reduce fever. Acetaminophen is used for pain and to reduce fever.”

Acetaminophen belongs to a class of drugs called analgesics. Ibuprofen belongs to the drug class called nonsteroidal anti-inflammatory drugs (NSAIDs). 

Forms

Ibuprofen and acetaminophen come in many different forms, including:

• oral tablets
• oral capsules
• oral suspension
• chewable tablets

Ibuprofen also comes in concentrated oral drops. Acetaminophen comes in these other forms:

• oral elixir
• oral solution
• extended-release oral tablets and caplets
• rectal suppositories
• rapid melt tablets
• effervescent tablets

Brand Names

Ibuprofen and acetaminophen are more commonly referred to as Tylenol and Advil. 

Brand Names for Acetaminophen & Ibuprofen